Protein factors tie the genome up in a bow for gene expression

Thursday, December 10, 2015 - 12:27 in Biology & Nature

Protein factors are responsible for organizing chromosomes inside the nucleus in three dimensions (3D), forming a shape like a gift bow, with proteins aggregating as the central 'knot' holding the ribbon-like loops of DNA when genes are organized for proper expression, or a tangled mess in the presence of certain mutations.

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