DNA bundles transform into stable chain-armor-like nanostructures by copper-catalyzed azide–alkyne click chemistry
Wednesday, June 3, 2015 - 05:10
in Physics & Chemistry
Short single strands of DNA can self-assemble to create DNA nanostructures. Scientists based in Munich, Germany, have prepared not only assembled, but even catenated oligonucleotide structures to form chain-armor DNA nanotubes that withstand high temperatures, and chemical and enzymatic attacks. As they report in the journal Angewandte Chemie, they used effective click chemistry to prepare the DNA catenane rings.