General principles to explain DNA brick self-assembly

Tuesday, May 19, 2015 - 08:31 in Biology & Nature

(Phys.org)—DNA bricks are an odd phenomenon. They are nanostructures built from synthetic, single-strand DNA that self-assemble into 3D structures. Several years ago, researchers at Wyss Institute at Harvard demonstrated the self-assembly of designed 3D structures made from 1,000 "bricks" that fit together like molecular Legos. One of the curiosities about these DNA bricks is why this complex self-assembly process works so well.

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