Molecular chaperones help with folding

Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding processes take place. A team of researchers at the University of Freiburg led by the assistant professor Dr. Thomas Becker worked with research groups led by Prof. Dr. Bettina Warscheid and Prof. Dr. Sabine Rospert in a study in which they discovered how these barrels, or protein machines, form. The scientists recently published their research results in the Journal of Biological Chemistry.

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