Researchers develop new tissue autofluorescence endoscopic technique
Tuesday, February 10, 2015 - 07:00
in Biology & Nature
Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide labelfree contrast between different types and states of tissue. Clinical FLIM can combine lifetime contrast with morphological information to provide a direct comparison between different spatial regions – making it easier to spot differences with respect to "normal" tissue, e.g. for diagnostic screening and potentially enabling margins of diseased tissue to be identified. To date, however, there have been relatively few clinical FLIM studies, partly due to a lack of suitable instrumentation.