Repairing DNA lesions
Wednesday, June 25, 2014 - 07:20
in Biology & Nature
Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ζ (Polζ) is a translesion DNA polymerases that repair DNA damage and relieve cell cycle arrest.