Formal mathematics underpins new approach that standardizes analysis of genome information
Wednesday, September 11, 2013 - 06:30
in Biology & Nature
Researchers in Singapore have developed and tested mathematical tools, or algorithms, that are more accurate and robust than those currently used in analyzing high-throughput genetic sequencing data. The algorithms can determine the location and activity of specific nucleic acid sequences in a broad range of high-throughput techniques that detect gene–protein interactions. The research group, led by Shyam Prabhakar of the A*STAR Genome Institute of Singapore, also showed they could use the algorithms to generate meaningful results from degraded tissue and tissue constructed from several different cell types.