Scientists discover Par-1 as a new component of the Hippo signaling pathway
Tuesday, August 6, 2013 - 16:20
in Biology & Nature
In the development of animals, which is closely controlled by diverse pathways, the regulation of organ size has been a long-standing puzzle. How does an organ ascertain its optimum size? What are the molecular mechanisms that stop organ growth at an appropriate point during development or regeneration? Almost a decade ago, the discovery of the Hippo signaling pathway provided an important starting point for answering these questions.