Researchers challenge long-held assumption of gene expression in embryonic stem cells
Wednesday, July 3, 2013 - 11:05
in Biology & Nature
Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self-renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers. This finding contradicts the field's presumptions about this important gene and its role in the differentiation of embryonic stem cells.