Cell membranes: Synthetics save time and cut costs
Wednesday, July 3, 2013 - 07:30
in Physics & Chemistry
Screening for critical drug targets known as G-protein-coupled receptors (GPCRs) is now possible without the need to extract these proteins from their native cells. Extraction requires the use of stabilizing lipids, which damage the structural integrity and functionality of GPCRs. The cell-free approach was developed by Madhavan Nallani from the A*STAR Institute of Materials Research and Engineering, Singapore, along with co-workers in Singapore, Germany and Austria.