Head in a cage: Fatty acid composition of diacylglycerols determines local signaling patterns

(Phys.org) —In the human body, lipids do not only serve as energy stores and structural elements, but they are also important signaling molecules. Disruptions of lipid signal transmission seem to be involved in diseases such as atherosclerosis and diabetes, as well as inflammation and pain. In the journal Angewandte Chemie, researchers from Heidelberg have now reported on photoactivatable lipids that can be used to manipulate signaling processes in cells with both spatial and time resolution.

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