Scientists use X-ray diffraction to image whole, hydrated cells in their natural state for the first time
Friday, May 17, 2013 - 08:30
in Physics & Chemistry
Most cells exist in a hydrated state and often live suspended in solution. In order to be imaged, cells must generally be frozen or dried, and then stained with substances such as heavy metals. Unfortunately, these processes can also alter the structure and chemical composition of the cells, resulting in inaccurate observations. Imaging the internal structures of whole, intact cells in their natural state has therefore been a particular challenge for scientists.