Resurrection of extinct enzymes reveals evolutionary strategy for the invention of new functions

Tuesday, December 11, 2012 - 17:00 in Biology & Nature

How does evolution innovate? We exist because our ancestors have had the ability to adapt successfully to changes in their environment; however, merely examining present-day organisms can limit our understanding of the actual evolutionary processes because the crucial events have been masked by the passage of aeons – what we need is a time machine. Scientists from VIB, KU Leuven, University of Ghent and Harvard have done the next-best thing; by reconstructing DNA and proteins from prehistoric yeast cells, they were able to directly examine the evolutionary forces that have acted over the last 100 million years to shape modern-day enzymes – biological catalysts that enable organisms to manipulate molecules to their will.

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