Anti-flu proteins work as designed, researchers confirm
Tuesday, October 2, 2012 - 08:00
in Physics & Chemistry
(Phys.org)—Understanding why proteins interact with certain specific molecules and not with the myriad others in their environment is a major goal of molecular biology. Now, in a series of recent papers, researchers describe how they designed proteins from scratch to have a high affinity and high specificity for targets on flu viruses, and then validated the two best designs using X-ray diffraction data collected at the Stanford Synchrotron Radiation Lightsource (SSRL).