The role of H3K9 in bringing order to the nucleus
Friday, August 31, 2012 - 09:00
in Physics & Chemistry
(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In a study published in the latest issue of Cell they show that at least two levels of histone H3 lysine 9 methylation trigger the anchoring of heterochromatin to the nuclear envelope.