Two proteins that regulate cell division co-operate to control neuronal differentiation
Thursday, August 2, 2012 - 07:32
in Biology & Nature
Researchers from the A*STAR Institute of Molecular and Cell Biology have identified components of the molecular mechanism that stops neural stem cells from dividing and then promotes their differentiation into different types of brain cells. During development of the nervous system, proteins called cyclin-dependent kinases (Cdks) tightly regulate the balance between the proliferation and differentiation of neural stem cells, but the exact role of each Cdk in these processes is not well understood.