Making sense of molecular fragments
Friday, June 29, 2012 - 07:01
in Biology & Nature
(Phys.org) -- Data from high-throughput next generation sequencers (NGS) and genome tiling arrays have greatly enhanced scientists ability to recreate RNA molecular structures, which is vital to disease and biotechnology research. However, high levels of noise and bias in some processes lead to uneven gene-expression values for segments belonging to the same molecule. Reconstructing the complete, or full-length, information of molecules as they occur in cells is therefore difficult.