Collective action: Occupied genetic switches hold clues to cells' history

Friday, February 3, 2012 - 11:31 in Biology & Nature

If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don't have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the molecules that activate those switches – transcription factors – can be used in a similar way, as clues to a cell's developmental history. The study, published today in Cell, also unveils a new model for how enhancers function.

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