Overcoming cancer drug resistance with nanoparticles
Friday, January 20, 2012 - 08:31
in Physics & Chemistry
One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University has found that biocompatible iron oxide-titanium dioxide nanoparticles can bypass this pump and enable DNA-damaging anticancer drugs to reach the cell nucleus.