The aldehyde dehydrogenase-2 polymorphism affects alcohol dependence differently by gender
Monday, August 15, 2011 - 15:32
in Psychology & Sociology
Researchers know that gender differences exist in the prevalence, characteristics, and course of alcohol dependence (AD). Polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are strong genetic determinants of AD. A new study of gender differences in the effects of these polymorphisms on the development of AD has found that inactive ALDH2 can accelerate the development of AD in women.