Linking brain-derived neurotrophic factor to alcohol dependence

Monday, August 15, 2011 - 15:32 in Health & Medicine

One of the ways an alcohol dependence (AD) diagnosis can be made is through measurement of biological markers of hepatic injury such as gamma glutamyl transferase (GGT) and mean corpuscular volume (MCV). These markers, however, are not always sufficiently sensitive or specific enough for determining AD, nor do their levels change rapidly in response to abstinence or relapse. A new study of brain-derived neurotrophic factor (BDNF), which regulates neuronal plasticity, indicates it may predict relapse in AD individuals undergoing treatment.

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