Low to moderate, not heavy, drinking releases 'feel-good' endorphins in the brain

Thursday, March 19, 2009 - 17:42 in Health & Medicine

Scientists know that alcohol affects the brain, but the specifics remain unclear. One possibility is that alcohol may increase or decrease the release and the synthesis of endogenous opioid peptides - endorphins, enkephalins and dynorphins - in distinct brain regions important for drug addiction. For the first time, a rodent study has confirmed that low to moderate levels of alcohol alter beta-endorphin release in the midbrain/Ventral Tegmental Area (VTA) region, producing the pleasant effects that likely reinforce alcohol consumption.

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