Protein predicts Gleevec resistance in gastrointestinal tumors

Friday, May 16, 2008 - 10:07 in Health & Medicine

Excess amounts of a protein called IGF-1R in patients with gastrointestinal stromal tumors (GISTs) could indicate that the patient would be less responsive to the drug imatinib mesylate (known as Gleevec), according to Andrew K. Godwin, Ph.D., a researcher at the Fox Chase Cancer Center in Philadelphia.

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