Effect of mutant p53 stability on tumorigenesis and drug design
Thursday, May 15, 2008 - 04:49
in Health & Medicine
In the May 15th issue of G&D, Dr. Guillermina Lozano (MD Anderson Cancer Center) and colleagues reveal how the stabilization of a mutated form of p53 affects oncogenesis, and lends startling new insight into the potential pitfalls of using Mdm2 inhibitors for cancer therapy.