Naturally Occurring Mechanism of Cancer Drug-Resistance May Itself Be a Treatment Target
Monday, December 26, 2016 - 16:31
in Health & Medicine
The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs. But Whitehead Institute researchers have found a mechanism underlying this resistance--a mechanism that naturally occurs in many diverse cancer types and that may expose vulnerabilities to drugs that spur the natural cell-death process.