UNC Researchers Discover "Master Regulator" Role for Little-Known Protein in Cancer Cells
Tuesday, April 29, 2014 - 13:00
in Health & Medicine
Researchers in the UNC School of Medicine found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several types of cancer cells from dividing and moving. The discovery, published in the journal Nature Communications, marks the first time this little-known protein has been characterized in relation to cancer development and tumor growth.