Researchers Link Aging to Cellular Interactions That Occur Across Generations

By studying the reproductive cells of nematodes - tiny worms found in soil and compost bins - Shawn Ahmed, PhD, an associate professor of genetics, identified the Piwi/piRNA genome silencing pathway, the loss of which results in infertility after many generations. He also found a signaling pathway - a series of molecular interactions inside cells - that he could tweak to overcome infertility while also causing the worms to live longer adult lives.

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