Prostate Cancer Gets Around Hormone Therapy by Activating a Survival Cell Signaling Pathway

In a study at UCLA's Jonsson Comprehensive Cancer Center, researchers found that when a common type of prostate cancer was treated with conventional hormone ablation therapy blocking androgen production or androgen receptor (AR) function- which drives growth of the tumor - the cancer was able to adapt and compensate by activating a survival cell signaling pathway, effectively circumventing the roadblock put up by this treatment.

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