Novel Genetic Screens Provide Panoramic Views of Cellular Systems

Thursday, October 16, 2008 - 13:21 in Biology & Nature

Researchers often use the technique of RNA interference (RNAi) to identify genes involved in particular biological processes by knocking them down, one at a time, and observing the result. But this approach fails to capture some key players because many genes are redundant. Thus, cells can mask their distress when they lose a single gene by turning to fail-safes with the same function. A team has now overcome this obstacle, using RNAi to systematically knock down pairs of genes in fruit fly cells.

Read the whole article on Newswise - Scinews

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