Persister Cell - How Bacterial Proteins Promote Antibiotic Resistance
Friday, October 30, 2015 - 01:50
in Health & Medicine
Scientists call them toxins but these bacterial proteins don't poison us, at least not directly. Instead, they restrain the growth of the bacteria that make them, establishing a dormant "persister cell" state that is tolerant to antibiotics. Researchers at Emory University School of Medicine have obtained precise pictures showing how a toxin protein, called HigB, recognizes and rips up RNA as part of its growth-inhibition function. Their findings could lead to a better understanding of the formation of persister cells and how they maintain themselves. read more