FGFR1 Gene Is The Conductor In The 'Symphony Of Biology'
Friday, May 8, 2015 - 13:40
in Biology & Nature
One of developmental biology's biggest mysteries is ontogeny and the signals that transform masses of undifferentiated cells into tremendously complex organisms. A new paper suggests that it all begins with a single "master" growth factor receptor, nuclear Fibroblast Growth Factor Receptor 1 (nFGFR1), that regulates the entire genome. The research using mouse embryonic stem cells hopes to challenge the supposition that specific types of growth factors only functioned at a cell's surface and that growth factors function from within the nucleus. read more