Stem-Cell-Based Therapy For Breast Cancer Metastases In The Brain Promising
Researchers have developed a mouse model of brain-metastatic breast cancer and found the potential of stem-cell-based therapy to eliminate metastatic cells from the brain and prolong survival is strong. The research team developed a mouse model that closely mimics what is seen in patients. They found that injecting into the carotid artery breast cancer cells that express markers allowing them to enter the brain - cells labeled with bioluminescent and fluorescent markers to enable tracking by imaging technologies - resulted in the formation of many metastatic tumors throughout the brain, mimicking what is seen in advanced breast cancer patients. Current therapeutic options for such patients are limited, particularly when there are many metastases. read more