Cancer Genes Turned Off In Deadly Brain Tumors By RNA Small Molecule

Wednesday, April 8, 2015 - 18:00 in Biology & Nature

Scientists have identified a small RNA molecule named miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.  There are 16,000 new cases of the deadly brain tumor reported in the U.S. every year. Patients have a very poor prognosis, with median survival of just 14 to 16 months. Standard chemotherapy drugs stop cancer cells from reproducing by damaging DNA but the new method instead stops the source that creates those cancer cells: genes that are overexpressing certain proteins. read more

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