Beta Secretase Inhibitors For Alzheimer's Disease
Sunday, April 5, 2015 - 15:40
in Health & Medicine
With each new amyloid-targeting treatment for Alzheimer's disease that has been developed, there has been a corresponding concern about antibodies targeting amyloid-β peptide (Aβ) producing inflammation in the brain in some patients. Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling. read more