Transport Molecule Forms A Protective Structure To Guide Proteins To Cell Membrane
Saturday, March 14, 2015 - 23:40
in Biology & Nature
The molecular complex that guides an important class of proteins to correct locations in cell membranes does so by forming a dimeric structure with a protective pocket, according to a new report. This structure shields tail-anchored membrane proteins - which have roles in a wide variety of cellular functions from neurotransmitter release to insulin production - from harmful aggregation or misfolding as they move through the inner environment of a cell. The findings clarify the mechanism behind a fundamental biological process. read more