How T Cells Cause Inflammation During Infections
Case Western Reserve University dental researcher Pushpa Pandiyan has discovered a new way to model how infection-fighting T cells cause inflammation in mice. The hope is that the discovery can lead to new therapies or drugs that jump-start weakened or poorly functioning immune systems, said Pandiyan, an assistant professor at Case Western Reserve School of Dental Medicine. Pandiyan believes the process could lead to identifying and testing new drugs to replace antifungal medicines that have become ineffective as the fungi develop a resistance to them. Pandiyan's findings are explained and demonstrated in the Journal of Visualized Experiments video and print article, "Th17 inflammation model of oropharyngeal candidiasis in immunodeficient mice." read more