How Pluripotent Stem Cells Are Grown Affects Their Genetic Stability

Wednesday, February 25, 2015 - 16:50 in Biology & Nature

Human pluripotent stem cells, which include both human embryonic stem cells(hESCs) and adult stem cells like induced pluripotent stem cells (iPSCs), need large numbers for transplantation into patients but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities, according to a new study.The authors say they have definitively shown that the culture conditions in which stem cells are grown and mass-produced can affect their genetic stability. read more

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