Blocking Notch Pathway To Help Restore Hearing
Monday, January 12, 2015 - 13:00
in Biology & Nature
Sensory 'hair cell' loss is the major cause of hearing loss and balance disorders. The postnatal mammalian inner ear harbors progenitor cells which have the potential for hair cell regeneration - and hearing recovery - but the mechanisms that control their proliferation and hair cell regeneration are yet to be determined. A new study has shown that blocking the Notch pathway, known to control the elaborate hair cell distribution in the inner ear, plays an essential role that determines cochlear progenitor cell proliferation capacity. read more