MTDH Breast Cancer Gene Needs A Partner To Create Tumors

Sunday, June 29, 2014 - 08:50 in Health & Medicine

The gene Metadherin - MTDH - which is implicated in promoting the spread of breast cancer tumors, only stimulates tumor growth when the protein made by the gene interacts with a second protein known as SND1, according to a paper in Cancer Cell. Invasive breast cancer strikes 1 in 8 women and causes roughly 40,000 deaths each year in the United States. About 20 percent of women with breast cancer go on to develop tumors that spread throughout body, are resistant to chemotherapy, and are often fatal. read more

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