"Tom Sawyer" Proteins Get Other Genes To Do The Work For Them

Friday, June 27, 2014 - 08:01 in Biology & Nature

Writing in the Proceedings of the National Academy of Sciences, scientists have shown regulatory proteins in the nucleus to adopt a kind of “Tom Sawyer” behavior when it comes to the work of initiating gene activation. Transcription factors are proteins that orchestrate the flow of genetic information from DNA to messenger RNA (mRNA) and the results show how transcription factors (TFs) activate mRNA synthesis of a gene, and leave the scene – in a model termed “hit-and-run” transcription. read more

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