Wnt Signaling Pathway: Link Between Colon Cancer And Metabolism
Tuesday, May 13, 2014 - 09:40
in Biology & Nature
More than 60 years ago, Otto Warburg said that cancer cells differ from normal cells in the metabolic pathway they use for the oxidation of sugar. Rather than the typical series of oxidative steps that take place in the citric acid cycle, cancer cells metabolize sugar via the glycolytic pathway irrespective of whether oxygen is present or not. Writing in a new paper for The EMBO Journal, researchers believe that the reason for this difference in colon cancer is changes in the Wnt signaling pathway, an essential communication pathway operating in these tumors. read more