New Cancer Therapies Linked To High Blood Pressure

Tuesday, May 6, 2014 - 14:11 in Health & Medicine

New cancer therapies, particularly agents that block vascular endothelial growth factor (VEGF) signaling, have been successful and are now used as a first line therapy for some tumors, but almost 100% of patients who take VEGF inhibitors (VEGFIs) develop high blood pressure, and a subset develops severe hypertension. The mechanisms underlying VEGF inhibitor-induced hypertension need to be better understood and there is a need for clear guidelines and improved management, say investigators behind the review in the Canadian Journal of Cardiology. read more

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