Amino Acid Fingerprints Revealed In New Study
Sunday, April 6, 2014 - 20:00
in Biology & Nature
Lindsay says that around 50 distinct signal burst characteristics were used in the amino acid identifications, but that most of the discriminatory power is achieved with 10 or fewer signal traits. Remarkably, recognition tunneling not only pinpointed amino acids with high reliability from single complex burst signals, but managed to distinguish a post-translationally modified protein (sarcosine) from its unmodified precursor (glycine) and also to discriminate between mirror-image molecules knows as enantiomers and so-called isobaric molecules, which differ in peptide sequence but exhibit identical masses. Pathway to the $1000 dollar proteome? read more