β-Amyloid Deposits Increase With Age, Associated With Artery Stiffness

Bottom Line: Stiffening of the arteries appears to be associated with the progressive buildup of β-amyloid (Αβ) plaque in the brains of elderly patients without dementia, suggesting a relationship between the severity of vascular disease and the plaque that is a hallmark of Alzheimer disease. Author: Timothy M. Hughes, Ph.D., M.P.H., of Wake Forest University, Winston-Salem, N.C., and colleagues. Background: Evidence suggested arterial stiffness is related to brain aging, cerebrovascular disease, impaired cognitive function and dementia in the elderly. read more

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