Validation Study Results Show Method Can Replace Live Animals In Skin Allergy Tests

Tuesday, March 25, 2014 - 21:40 in Biology & Nature

Phoenix — Guinea pigs and mice can be replaced with a non-animal skin sensitization method that uses a human-derived skin model, according to a study presented today by the PETA International Science Consortium, Ltd., at the Society of Toxicology's annual meeting. Recent results show that Cyprotex's in vitro skin sensitization assay SenCeeTox® can correctly identify chemicals that cause an allergic response in humans and, unlike many other methods, can predict the potency of the response. This non-animal method uses a three-dimensional, human-derived skin model that accurately replicates many of the key traits of normal human skin, allowing it to be used to test finished products such as gels and creams. read more

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