Genetic Background Of Sporadic Amyotrophic Lateral Sclerosis In The Chinese Han Population
Saturday, March 1, 2014 - 10:30
in Health & Medicine
A previous study of European Caucasian patients with sporadic amyotrophic lateral sclerosis demonstrated that a polymorphism in the microtubule-associated protein Tau (MAPT) gene was significantly associated with sporadic amyotrophic lateral sclerosis pathogenesis. To examine this in a different population, Daojun Hong and colleagues from Nanchang University further investigated the association of the MAPT gene with sporadic amyotrophic lateral sclerosis in the Chinese Han population. Researchers detected two genetic variations in MAPT (105788 A > G in intron 9 and 123972 T > A in intron 11) in sporadic amyotrophic lateral sclerosis patients but not controls. read more