PHPS1 Compound Improves Cardiac Function In Mice With Congenital Heart Disease

Friday, February 28, 2014 - 04:50 in Health & Medicine

Congenital heart disease is the most common form of birth defect, affecting one out of every 125 babies, according to the National Institutes of Health. Researchers from the University of Missouri recently found success using chemical compound  PHPS1 to treat laboratory mice with one form of congenital heart disease, hypertrophic cardiomyopathy — a weakening of the heart caused by abnormally thick muscle. By suppressing a faulty protein, the researchers reduced the thickness of the mice's heart muscles and improved their cardiac functioning. read more

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