Target Acquired: 'Undruggable' Protein K-Ras Meets Its Match
Thursday, November 21, 2013 - 14:50
in Biology & Nature
In drug design, the protein K-Ras has been on everyone's target list for more than 30 years due to its status as the most commonly mutated oncogene in human cancers. Despite its high profile, K-Ras has been "undruggable" - many pharmaceutical, biotech, and academic laboratories have failed to design a drug that successfully targets the mutant gene. read more