Hypoxia Reason Why One Anti-Cancer Therapy Stops Working
Monday, June 24, 2013 - 10:50
in Health & Medicine
A promising anti-cancer therapy - suppression of the protein mammalian target Of Rapamycin (mTOR) - has failed to achieve hoped-for success in killing tumor cells. mTOR plays an important role in regulating how cells process molecular signals from their environment, and it is observed as strongly activated in many solid cancers. Drug-induced suppression of mTOR has until now shown success in causing the death of cancer cells in the outer layers of cancerous tumors, but has been disappointing in clinical trials in dealing with the core of those tumors. read more