A Treatment At Last For Machado-Joseph Disease ?
Monday, July 23, 2012 - 07:02
in Health & Medicine
Researchers have moved a step closer to find a treatment for the fatal neurodegenerative disorder Machado-Joseph disease (MJD) after a Portuguese team fromthe Centre for Neurosciences at the University of Coimbra was able tohalt the brain degeneration in mice, by blocking a molecule called calpain. Calpain are known to cut ataxin-3 (the mutant protein behind MJD) into fragments, and the study, which will be published in the journal Brain, proves that these fragments are crucialto trigger the neurodegeneration. read more